Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789401 | 0.86 | POLB (0.44) | KDM4EHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL28007224 | 0.83 | MAOA (0.52) | KDM4EHPGDNPSR1ALDH1A1STAT3 | |
| SCHEMBL2015417 | 0.79 | HIF1A (0.43) | KDM4EHPGDNPSR1ALDH1A1STAT3 | |
| SCHEMBL8786112 | 0.76 | RAB9A (0.43) | KDM4EHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL3932873 | 0.75 | KDM4E (0.47) | KDM4EHPGDNPSR1ALDH1A1STAT3 | |
| SCHEMBL12490166 | 0.75 | MAPT (0.45) | KDM4EALDH1A1HIF1AMEN1KMT2A | |
| SCHEMBL7016481 | 0.74 | LMNA (0.51) | KDM4ENPSR1ALDH1A1STAT3HIF1A | |
| SCHEMBL8789407 | 0.74 | POLB (0.42) | KDM4EHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL29829038 | 0.73 | NCEH1 (0.48) | KDM4EHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL27032878 | 0.73 | NCEH1 (0.48) | KDM4EHPGDNPSR1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658933-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-08-19 | — | — | US | disclosed |