Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 9/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | HPD | P32754 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165760 | 0.85 | FFAR1 (0.35) | MAOAMAOBHTR6HPDMAPT | |
| SCHEMBL5607419 | 0.75 | HTR1A (0.42) | HTR1ADRD2 | |
| SCHEMBL15822590 | 0.73 | TACR1 (0.33) | RXRARXRBRXRGTACR1 | |
| SCHEMBL3657142 | 0.73 | HTR1A (0.42) | HTR1ADRD2 | |
| SCHEMBL2417663 | 0.72 | HTR1A (0.44) | HTR1ADRD2 | |
| SCHEMBL7606129 | 0.71 | DRD2 (0.57) | HTR1ADRD2 | |
| SCHEMBL11166219 | 0.68 | ADRB2 (0.50) | RXRARXRBMAPTMAPK1TDP1 | |
| SCHEMBL11196145 | 0.68 | ADRB2 (0.50) | RXRARXRBMAPTMAPK1TDP1 | |
| SCHEMBL11173983 | 0.68 | ADRB2 (0.50) | RXRARXRBMAPTMAPK1TDP1 | |
| SCHEMBL11173989 | 0.68 | ADRB2 (0.50) | RXRARXRBMAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541823-A1 | CATALYSTS | Borealis AG (AT) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018091684-A1 | CATALYSTS | BOREALIS AG (AT) | 2018-05-24 | — | — | WO | disclosed |