Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2417663 | 0.92 | HTR1A (0.44) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL5607419 | 0.87 | HTR1A (0.42) | HTR1AHTR1DHTR1BDRD2ADRB2 | |
| SCHEMBL7606129 | 0.75 | DRD2 (0.57) | HTR1ADRD2DRD3 | |
| SCHEMBL2416358 | 0.73 | RXRB (0.50) | — | |
| SCHEMBL20165699 | 0.73 | RXRA (0.41) | HTR1ADRD2 | |
| SCHEMBL5606539 | 0.70 | ADRA1A (0.36) | ADRA1A | |
| SCHEMBL24650451 | 0.68 | DRD2 (0.46) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL12634478 | 0.68 | CYP19A1 (0.43) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL6795825 | 0.68 | KDM4E (0.54) | HTR1BRECQLLMNA | |
| SCHEMBL29755815 | 0.68 | KDM4E (0.54) | HTR1BRECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2215129-A2 | CATALYSTS | Borealis Technology OY (FI) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009027075-A2 | CATALYSTS | BOREALIS TECHNOLOGY OY (FI) | 2009-03-05 | — | — | WO | disclosed |