SCHEMBL20165817

SCHEMBL20165817

COc1c(C(C)(C)C)cc2c(c1-c1cc(C)cc(C)c1)C=C(C)[CH]2

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.32
PTGS1 P23219 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CNR2 P34972 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27076840 0.99 PTGS2 (0.32) PTGS2PTGS1ALDH1A1TSHRTDP1
SCHEMBL23291106 0.95 PTGS2 (0.32) PTGS2PTGS1
SCHEMBL21550601 0.95
SCHEMBL25335426 0.92 PTGS2 (0.39) PTGS2PTGS1ALDH1A1TSHRTDP1
SCHEMBL28435790 0.89 PTGS2 (0.32) PTGS2PTGS1ALDH1A1TSHRTDP1
SCHEMBL14645993 0.88 PTGS2 (0.32) PTGS2PTGS1ALDH1A1TSHRTDP1
SCHEMBL14645800 0.85 PDE4B (0.40) PTGS2ALDH1A1TSHRTDP1
SCHEMBL14645974 0.84 TDO2 (0.33) PTGS2ALDH1A1TSHRTDP1
SCHEMBL28934021 0.83
SCHEMBL28013344 0.81 PDE4B (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4281206-A1 ELECTRET MELT-BLOWN WEBS WITH IMPROVED FILTRATION PROPERTIES Borealis AG (AT) 2023-11-29 EP disclosed
WO-2023099451-A1 HIGH MELT FLOW POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-06-08 WO disclosed
WO-2023099448-A1 POLYPROPYLENE COMPOSITION SUITABLE FOR PACKAGING APPLICATIONS BOREALIS AG (AT) 2023-06-08 WO disclosed
EP-3820939-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH IMPROVED BALANCE OF PROPERTIES Borealis AG (AT) 2021-05-19 EP disclosed
WO-2020011825-A1 HETEROPHASIC POLYPROPYLENE COMPOSITION WITH IMPROVED BALANCE OF PROPERTIES BOREALIS AG (AT) 2020-01-16 WO disclosed
EP-3562831-A1 CATALYSTS Borealis AG (AT) 2019-11-06 EP disclosed
EP-3541823-A1 CATALYSTS Borealis AG (AT) 2019-09-25 EP disclosed
WO-2018122134-A1 CATALYSTS BOREALIS AG (AT) 2018-07-05 WO disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed