SCHEMBL28013344

SCHEMBL28013344

COc1c(C(C)(C)C)cc2c(c1-c1ccccc1)C=C(C)[CH]2.Cl[Zr]Cl

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 4/20 0.36
PDE4A P27815 3/20 0.36
PDE4C Q08493 3/20 0.36
PDE4D Q08499 3/20 0.36
TNFRSF1A P19438 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14645800 0.95 PDE4B (0.40) PDE4BPDE4APDE4CPDE4DTNFRSF1A
SCHEMBL20340256 0.89 TDO2 (0.31)
SCHEMBL21550601 0.86
SCHEMBL28934021 0.85
SCHEMBL14645974 0.84 TDO2 (0.33)
SCHEMBL25335426 0.83 PTGS2 (0.39)
SCHEMBL28779169 0.82 PDE4A (0.35) PDE4BPDE4APDE4CPDE4D
SCHEMBL23290964 0.82 TDO2 (0.31)
SCHEMBL20165817 0.81 PTGS2 (0.32)
SCHEMBL25337017 0.80 EGFR (0.33) TNFRSF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112639011-A Propylene copolymer compositions having excellent optical and mechanical properties 博里利斯股份公司 2021-04-09 CN disclosed
CN-109312511-B Meltblown webs having good water repellency properties 北欧化工公司 2020-09-01 CN disclosed
CN-109312511-A Melt-blow fiber web with good waterproof performance 北欧化工公司 2019-02-05 CN disclosed
CN-103608177-B Multi-layer biaxially oriented polymer film BOREALIS AG 2015-06-24 CN disclosed