SCHEMBL20165822

SCHEMBL20165822

CC1=Cc2cc(C)cc(-c3cc(C)cc(C)c3)c2C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
BRD9 Q9H8M2 1/20 0.31
BRD7 Q9NPI1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20165781 0.80 BRD9 (0.35) MEN1KMT2ABRD9BRD7
SCHEMBL19393460 0.79 LMNA (0.33)
SCHEMBL15808729 0.79 PTAFR (0.39)
SCHEMBL2972383 0.72
SCHEMBL31355504 0.72 BRD9 (0.33) MEN1KMT2ABRD9BRD7
SCHEMBL31355503 0.72 BRD9 (0.33) MEN1KMT2ABRD9BRD7
SCHEMBL15809151 0.72 KDM4E (0.32)
SCHEMBL2481681 0.70 CYP2A6 (0.37) MEN1KMT2A
SCHEMBL2971639 0.70 ALDH1A1 (0.33)
SCHEMBL28314871 0.69 BRD9 (0.34) MEN1KMT2ABRD9BRD7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11981801-B2 Polypropylene composition BOREALIS AG (AT) 2024-05-14 US disclosed
US-20230242748-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2023-08-03 US disclosed
CN-110770264-B Process for preparing heterophasic propylene copolymers 博里利斯股份公司 2022-10-14 CN disclosed
CN-110177798-B Catalyst and process for preparing same 博里利斯股份公司 2022-08-30 CN disclosed
US-11352376-B2 Catalysts BOREALIS AG (AT) 2022-06-07 US disclosed
CN-110741039-B Polypropylene composition 博里利斯股份公司 2022-02-18 CN disclosed
US-11078304-B2 Process for preparing heterophasic propylene copolymers BOREALIS AG (AT) 2021-08-03 US disclosed
EP-3541823-B1 CATALYSTS BOREALIS AG (AT) 2020-12-30 EP disclosed
EP-3652247-A1 POLYPROPYLENE COMPOSITION Borealis AG (AT) 2020-05-20 EP disclosed
US-20200131284-A1 PROCESS FOR THE PREPARING HETEROPHASIC PROPYLENE COPOLYMERS BOREALIS AG (AT) 2020-04-30 US disclosed
CN-110770264-A Process for preparing heterophasic propylene copolymers 博里利斯股份公司 2020-02-07 CN disclosed
CN-110741039-A Polypropylene composition 博里利斯股份公司 2020-01-31 CN disclosed
US-20190308995-A1 CATALYSTS BOREALIS AG (AT) 2019-10-10 US disclosed
EP-3541823-A1 CATALYSTS Borealis AG (AT) 2019-09-25 EP disclosed
CN-110177798-A Catalyst 博里利斯股份公司 2019-08-27 CN disclosed
WO-2019012110-A1 POLYPROPYLENE COMPOSITION BOREALIS AG (AT) 2019-01-17 WO disclosed
WO-2018091684-A1 CATALYSTS BOREALIS AG (AT) 2018-05-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11352376-B2 Catalysts SIGMAR1, H1-2, SFN MEN1 1490/4885KMT2A 473/4885BRD9 1797/4885
US-20190308995-A1 CATALYSTS SIGMAR1, H1-2, CBR1 MEN1 1642/4885KMT2A 406/4885BRD9 1700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.