Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 9/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.57 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.57 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502497 | 1.00 | LMNA (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30192728 | 0.98 | PKM (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29117384 | 0.98 | PKM (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27726840 | 0.98 | PKM (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8729265 | 0.84 | LMNA (0.57) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28050241 | 0.83 | RAB9A (0.68) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28728369 | 0.81 | RAB9A (0.66) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14380967 | 0.79 | CYP3A4 (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1800355 | 0.79 | CYP3A4 (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29647608 | 0.79 | CYP3A4 (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836382-A | Halogen-free antibacterial polyamide and preparation method thereof | 四川轻化工大学 | 2023-10-03 | — | — | CN | claimed |
| CN-106337196-B | Microscopic void sealer for the processing of printed wiring board precious metal surface | 深圳市贝加电子材料有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-106337196-A | Micro pore sealing agent for noble metal surface treatment of printed circuit board | 深圳市贝加电子材料有限公司 | 2017-01-18 | — | — | CN | claimed |
| EP-2445346-A1 | OXO-HETEROCYCLE FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | Genentech, Inc. (US) | 2012-05-02 | — | — | EP | claimed |
| WO-2010151601-A1 | OXO-HETEROCYCLE FUSED PYRIMIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE | GENENTECH, INC. (US) | 2010-12-29 | — | — | WO | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| CN-1034216-C | 7-(substituted)-9-[(substituted glycyl) amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 1997-03-12 | — | — | CN | claimed |
| EP-0594656-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1994-05-04 | — | — | EP | claimed |
| CN-1083805-A | 7-(replacement)-9-[(substituted glycyl) amido]-6-demethylation-6-deoxytetra cycline | AMERICAN CYANAMID CO (US) | 1994-03-16 | — | — | CN | claimed |
| WO-1993001166-A1 | 4-AMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1993-01-21 | — | — | WO | claimed |
| US-12435095-B2 | Substituted morpholines as ATR kinase inhibitors | SHANGHAI ANNOVA BIOTECHNOLOGY CO., LTD. (CN) | 2025-10-07 | — | — | US | disclosed |
| US-20250051362-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANGHAI ANNOVA BIOTECHNOLOGY CO., LTD. (CN) | 2025-02-13 | — | — | US | disclosed |
| EP-4455144-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Annova Biotechnology Co., Ltd. (CN) | 2024-10-30 | — | — | EP | disclosed |
| CN-117751127-A | Five-membered nitrogen-containing heterocyclic heteroaryl derivative and application thereof | 南京大美生物制药有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2024017897-A1 | 1,3,4-OXADIAZOLE DERIVATIVES AS SELECTIVE HISTONE DEACETYLASE 6 INHIBITORS | ITALFARMACO S.P.A. (IT) | 2024-01-25 | — | — | WO | disclosed |
| US-5760029-A | TREATING CANCER METASTASIS, DIABETIC RETINOPATHY, NEOVASCULAR GLAUCOMA, THROMBOSIS, RESTENOSIS, OSTEOPOROSIS, MACULAR DEGENERATION | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-06-02 | — | — | US | disclosed |
| CN-1034216-C | 7-(substituted)-9-[(substituted glycyl) amido]-6-demethyl-6-deoxytetracyclines | AMERICAN CYANAMID CO (US) | 1997-03-12 | — | — | CN | disclosed |
| CN-1087626-A | The glycyl that novel 7-(replacement)-8-(replacement)-9-[(replaces) amido]-6-demethyl-6-deoxidation tsiklomitsin | AMERICAN CYANAMID CO (US) | 1994-06-08 | — | — | CN | disclosed |
| CN-1083805-A | 7-(replacement)-9-[(substituted glycyl) amido]-6-demethylation-6-deoxytetra cycline | AMERICAN CYANAMID CO (US) | 1994-03-16 | — | — | CN | disclosed |
| US-4167569-A | ANTICOAGULANTS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12435095-B2 | Substituted morpholines as ATR kinase inhibitors | ATR, WEE1, WEE2 | LMNA 2546/4885PKM 1002/4885RAB9A 2504/4885 |
| US-20250051362-A1 | SUBSTITUTED FUSED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | WEE1, ATR, WEE2 | LMNA 2829/4885PKM 2313/4885RAB9A 1862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.