Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.54 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.54 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502497 | 0.84 | LMNA (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2016737 | 0.84 | LMNA (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30192728 | 0.82 | PKM (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27726840 | 0.82 | PKM (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29117384 | 0.82 | PKM (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28050241 | 0.79 | RAB9A (0.68) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28728369 | 0.78 | RAB9A (0.66) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1800355 | 0.76 | CYP3A4 (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL14380967 | 0.76 | CYP3A4 (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29647608 | 0.76 | CYP3A4 (0.61) | LMNAPKMRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |