Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 17/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.31 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168796 | 0.83 | MGLL (0.41) | MGLLABHD6 | |
| SCHEMBL29561179 | 0.82 | MGLL (0.65) | MGLLABHD6PLA2G7 | |
| SCHEMBL20137074 | 0.82 | MGLL (0.65) | MGLLABHD6PLA2G7 | |
| SCHEMBL20168740 | 0.82 | MGLL (0.66) | MGLLABHD6 | |
| SCHEMBL20168794 | 0.80 | MGLL (0.44) | MGLLABHD6PLA2G7 | |
| SCHEMBL20137052 | 0.76 | MGLL (0.67) | MGLLABHD6PLA2G7 | |
| SCHEMBL20179549 | 0.75 | MGLL (0.34) | MGLLABHD6PLA2G7 | |
| SCHEMBL20151849 | 0.75 | MGLL (0.56) | MGLLABHD6PLA2G7 | |
| SCHEMBL20137125 | 0.75 | MGLL (0.39) | MGLLSLC6A4ALDH1A1 | |
| SCHEMBL20166773 | 0.74 | MGLL (0.46) | MGLLALDH1A1SMN1; SMN2ABHD6PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |