Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 8/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | F9 | P00740 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | F12 | P00748 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | F7 | P08709 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.32 |
| ▸ | MC4R | P32245 | 4/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168796 | 0.92 | MGLL (0.41) | MGLLABHD6EPHX2 | |
| SCHEMBL20137409 | 0.82 | MGLL (0.52) | MGLLABHD6PLA2G7 | |
| SCHEMBL29531615 | 0.82 | MGLL (0.52) | MGLLABHD6PLA2G7 | |
| SCHEMBL15094631 | 0.77 | MMP1 (0.40) | MGLLABHD6PLA2G7 | |
| SCHEMBL20168514 | 0.75 | MGLL (0.44) | MGLLABHD6PLA2G7 | |
| SCHEMBL20150069 | 0.75 | MGLL (0.53) | MGLLABHD6PLA2G7 | |
| SCHEMBL20136986 | 0.74 | MGLL (0.62) | MGLLABHD6PLA2G7 | |
| SCHEMBL29531245 | 0.74 | MGLL (0.62) | MGLLABHD6PLA2G7 | |
| SCHEMBL20168767 | 0.73 | MGLL (0.49) | MGLLABHD6 | |
| SCHEMBL20151855 | 0.73 | MGLL (0.54) | MGLLABHD6PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541822-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093946-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |