Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20179549 | 0.92 | MGLL (0.34) | MGLLEPHX2ABHD6 | |
| SCHEMBL20168514 | 0.83 | MGLL (0.44) | MGLLABHD6 | |
| SCHEMBL20136986 | 0.82 | MGLL (0.62) | MGLLCYP2D6ABHD6 | |
| SCHEMBL29531245 | 0.82 | MGLL (0.62) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20137383 | 0.81 | MGLL (0.52) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20168767 | 0.81 | MGLL (0.49) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20168799 | 0.79 | MGLL (0.65) | MGLLCYP2D6ABHD6 | |
| SCHEMBL20166173 | 0.79 | MGLL (0.39) | MGLLRXRANR1H2MEN1KMT2A | |
| SCHEMBL20179522 | 0.78 | MGLL (0.56) | MGLL | |
| SCHEMBL29531297 | 0.78 | MGLL (0.47) | MGLLRXRANR1H2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541822-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093946-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |