SCHEMBL2016857

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22605710	0.85	MAPK1 (0.57)	MAPK1GPR119MEN1KMT2AKDM4E
	SCHEMBL2016217	0.85	CNR1 (0.44)	MAPK1USP30SMARCA2SMARCA4PBRM1
	SCHEMBL2013371	0.85	FPR2 (0.45)	MAPK1USP30SMARCA2SMARCA4PBRM1
	SCHEMBL31543797	0.85	FPR2 (0.45)	MAPK1USP30SMARCA2SMARCA4PBRM1
	SCHEMBL1351555	0.84	MAPK1 (0.47)	MAPK1USP30SMARCA2SMARCA4PBRM1
	SCHEMBL1350836	0.83	SIGMAR1 (0.45)	MAPK1USP30SMARCA2SMARCA4PBRM1
	SCHEMBL2013375	0.83	SIGMAR1 (0.45)	MAPK1USP30SMARCA2SMARCA4PBRM1
	SCHEMBL2014317	0.82	KDM4E (0.43)	MAPK1USP30SMARCA2SMARCA4PBRM1
	SCHEMBL29586410	0.80	MAPT (0.46)	MAPK1USP30SMARCA2SMARCA4PBRM1
	SCHEMBL24187402	0.80	SIGMAR1 (0.65)	MAPK1USP30SMARCA2SMARCA4PBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.