Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 14/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20136985 | 0.80 | MGLL (0.62) | MGLL | |
| SCHEMBL20137135 | 0.73 | MGLL (0.51) | MGLLPTGDR2 | |
| SCHEMBL4108586 | 0.69 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL20136944 | 0.67 | ALOX5AP (0.40) | MGLLALOX5APFEN1 | |
| SCHEMBL3773661 | 0.67 | AGTR2 (0.50) | — | |
| SCHEMBL1713555 | 0.67 | PTGDR2 (0.56) | PTGDR2 | |
| SCHEMBL4114701 | 0.67 | PTGDR2 (0.63) | MGLLPTGDR2 | |
| SCHEMBL20137051 | 0.67 | MGLL (0.63) | MGLL | |
| SCHEMBL1714986 | 0.66 | PTGDR2 (0.57) | PTGDR2 | |
| SCHEMBL21996912 | 0.66 | S1PR5 (0.40) | MGLLPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541821-A1 | MAGL INHIBITORS | Abide Therapeutics, Inc. (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018093947-A1 | MAGL INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-05-24 | — | — | WO | disclosed |