SCHEMBL20168885

SCHEMBL20168885

CCCCOC(=O)CC(C)N(CC)C(=O)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.39
ALDH1A1 P00352 2/20 0.38
NPSR1 Q6W5P4 2/20 0.36
MAPK1 P28482 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 1/20 0.36
ATM Q13315 1/20 0.36
DGKA P23743 1/20 0.35
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
RAD52 P43351 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
FAAH O00519 1/20 0.33
DNM1 Q05193 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
HSD17B10 Q99714 1/20 0.33
HTR2C P28335 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21522866 0.91 ALDH1A1 (0.34) NAAAALDH1A1L3MBTL1DGKALMNA
SCHEMBL21522905 0.88 NAAA (0.37) NAAAALDH1A1NPSR1MAPK1L3MBTL1
SCHEMBL20180239 0.87 MGAM (0.40) ALDH1A1L3MBTL1TSHRLMNAPOLB
SCHEMBL20165345 0.84 ALDH1A1 (0.37) NAAAALDH1A1NPSR1MAPK1L3MBTL1
SCHEMBL21522901 0.84 DNM1 (0.36) NAAAALDH1A1NPSR1MAPK1L3MBTL1
SCHEMBL21522845 0.83 NAAA (0.40) NAAAALDH1A1NPSR1MAPK1L3MBTL1
SCHEMBL21522908 0.82 NAAA (0.39) NAAAALDH1A1NPSR1MAPK1L3MBTL1
SCHEMBL20168886 0.81 ALDH1A1 (0.37) ALDH1A1L3MBTL1MAPTTSHRDNM1
SCHEMBL21522875 0.81 L3MBTL1 (0.34) ALDH1A1L3MBTL1TSHRLMNAPOLB
SCHEMBL20166077 0.79 ALDH1A1 (0.33) ALDH1A1L3MBTL1LMNAPOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3541857-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2020-09-09 EP disclosed
US-10654946-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2020-05-19 US disclosed
US-20190330388-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2019-10-31 US disclosed
EP-3541857-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2019-09-25 EP disclosed
WO-2018091375-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-05-24 WO disclosed