Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168992 | 0.85 | MMP2 (0.32) | — | |
| SCHEMBL20969263 | 0.84 | ALDH1A1 (0.46) | KDM4EMEN1MAPTKMT2ANPC1 | |
| SCHEMBL20969156 | 0.82 | CHRM3 (0.40) | CHRM1MEN1KMT2ANPC1POLB | |
| SCHEMBL17865736 | 0.82 | CHRM1 (0.38) | CHRM1HSD11B1KDM4EMEN1MAPT | |
| SCHEMBL20153492 | 0.82 | CHRM1 (0.38) | CHRM1HSD11B1KDM4EMEN1MAPT | |
| SCHEMBL17865766 | 0.82 | CHRM1 (0.38) | CHRM1HSD11B1KDM4EMEN1MAPT | |
| SCHEMBL20969153 | 0.76 | ADAMTS5 (0.50) | HRH3 | |
| SCHEMBL19521198 | 0.75 | HTT (0.35) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL20969181 | 0.74 | CCR1 (0.42) | HSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL19521178 | 0.74 | ALDH1A1 (0.44) | KDM4EMEN1MAPTKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975879-B2 | Beta lactams as modulators of glutamate uptake and methods for use thereof | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-22 | — | — | US | disclosed |