Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169007 | 0.85 | CHRM1 (0.38) | — | |
| SCHEMBL20969263 | 0.85 | ALDH1A1 (0.46) | — | |
| SCHEMBL20969156 | 0.83 | CHRM3 (0.40) | — | |
| SCHEMBL17865745 | 0.80 | MMP2 (0.33) | MMP2ADAM17ADAMTS5 | |
| SCHEMBL20153497 | 0.80 | MMP2 (0.33) | MMP2ADAM17ADAMTS5 | |
| SCHEMBL17865757 | 0.80 | MMP2 (0.33) | MMP2ADAM17ADAMTS5 | |
| SCHEMBL20969153 | 0.77 | ADAMTS5 (0.50) | ADAMTS5 | |
| SCHEMBL19521198 | 0.76 | HTT (0.35) | MMP2ADAM17ADAMTS5 | |
| SCHEMBL20969181 | 0.75 | CCR1 (0.42) | — | |
| SCHEMBL19521178 | 0.75 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975879-B2 | Beta lactams as modulators of glutamate uptake and methods for use thereof | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2018-05-22 | — | — | US | disclosed |