Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | VDR | P11473 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017286 | 0.88 | MAPT (0.56) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL9779937 | 0.87 | NPC1 (0.50) | ALDH1A1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL16887793 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL3841711 | 0.78 | LMNA (0.55) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL20941779 | 0.77 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL20941589 | 0.77 | MAPT (0.61) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL9779960 | 0.76 | MAPT (0.53) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL20941597 | 0.76 | ALDH1A1 (0.76) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL20942397 | 0.76 | ALDH1A1 (0.60) | ALDH1A1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL27626623 | 0.76 | MCL1 (0.56) | ALDH1A1MAPTKMT2AMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10766882-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM CO., LTD. (KR) | 2020-09-08 | — | — | US | disclosed |
| US-9975883-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM. CO., LTD. (KR) | 2018-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766882-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | CYP2S1, GYS2, SLC5A1 | ALDH1A1 688/4885MAPT 141/4885KMT2A 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.