Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065085 | 0.84 | PPARG (0.44) | SLC6A4PPARGPPARAKDM4ELTA4H | |
| SCHEMBL7960172 | 0.83 | TSHR (0.42) | SLC6A4PPARGPPARAKDM4ELTA4H | |
| SCHEMBL5323618 | 0.81 | SLC7A5 (0.43) | SLC6A4PPARGPPARALTA4HSLC7A5 | |
| SCHEMBL10933718 | 0.81 | SLC6A4 (0.39) | SLC6A4PPARGPPARAKDM4ELTA4H | |
| SCHEMBL27438936 | 0.81 | LTA4H (0.44) | SLC6A4PPARGPPARAKDM4ELTA4H | |
| SCHEMBL9543123 | 0.80 | MTNR1A (0.40) | SLC6A4PPARGPPARAKDM4ELTA4H | |
| SCHEMBL9992781 | 0.79 | LTA4H (0.44) | SLC6A4PPARGPPARALTA4HSLC7A5 | |
| SCHEMBL1455125 | 0.78 | SLC6A4 (0.37) | SLC6A4PPARGPPARAKDM4ELTA4H | |
| SCHEMBL5280440 | 0.78 | SLC7A5 (0.48) | SLC6A4SLC7A5 | |
| SCHEMBL8766939 | 0.78 | LTA4H (0.43) | SLC6A4LTA4HSLC7A5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975906-B2 | Tricyclic heterocycle derivatives having HIV replication inhibitory effect | SHIONOGI & CO., LTD. (JP) | 2018-05-22 | — | — | US | disclosed |