Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064880 | 0.81 | MASP2 (0.60) | MASP2DRD2HTR2AHTR6HTR7 | |
| Hydrochloric Acid SCHEMBL4302262 | 0.79 | MASP2 (0.58) | MASP2DRD2HTR2AHTR6HTR7 | |
| SCHEMBL30753500 | 0.79 | MASP2 (0.44) | MASP2NPY5RDRD2HTR2AHTR6 | |
| SCHEMBL13665045 | 0.78 | MASP2 (0.72) | MASP2NPY5RDRD2HTR2AHTR6 | |
| SCHEMBL13664538 | 0.75 | DRD2 (0.49) | MASP2DRD2HTR2AHTR6HTR7 | |
| SCHEMBL4064876 | 0.73 | MASP2 (0.50) | MASP2DRD2HTR2AHTR6HTR7 | |
| SCHEMBL725351 | 0.72 | MASP2 (1.00) | MASP2NPY5RAOC3RAB9ALTA4H | |
| SCHEMBL20169733 | 0.72 | ALDH1A1 (0.48) | MASP2AOC3SMN1; SMN2HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL4302259 | 0.71 | MASP2 (0.49) | MASP2DRD2HTR2AHTR6HTR7 | |
| SCHEMBL14291616 | 0.71 | MASP2 (0.49) | MASP2DRD2HTR2AHTR6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975857-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-05-22 | — | — | US | disclosed |