Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19677016 | 0.80 | ALDH1A1 (0.36) | ALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL23987796 | 0.79 | PHF8 (0.42) | MAPTALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL23612436 | 0.76 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL19336086 | 0.76 | MAPT (0.44) | MAPTALDH1A1KMT2AFAAHNPSR1 | |
| SCHEMBL5147801 | 0.75 | ALDH1A1 (0.59) | MAPTALDH1A1KMT2AFAAHNPSR1 | |
| SCHEMBL2933508 | 0.75 | ZDHHC20 (0.50) | MAPTALDH1A1KMT2AFAAHNPSR1 | |
| SCHEMBL27604271 | 0.73 | MAPT (0.60) | MAPTALDH1A1KMT2AFAAHNPSR1 | |
| SCHEMBL13357724 | 0.73 | FAAH (0.46) | ALDH1A1KMT2AFAAHMEN1SMN1; SMN2 | |
| SCHEMBL21203195 | 0.71 | — | — | |
| Propene SCHEMBL29262705 | 0.71 | FAAH (0.61) | MAPTALDH1A1KMT2AFAAHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323817-A1 | ANILINE PYRIMIDINE DERIVATIVES AND USES THEREOF | Chia Tai Tianqing Pharmaceutical Group Co.,Ltd (CN) | 2018-05-23 | — | — | EP | disclosed |