Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170669 | 1.00 | ADRA1A (0.34) | ADRA1ANQO2MTNR1AMTNR1BOPRM1 | |
| SCHEMBL20170882 | 0.79 | — | — | |
| SCHEMBL20170697 | 0.77 | HTR1A (0.34) | OPRM1HTR1A | |
| SCHEMBL20170645 | 0.77 | OPRM1 (0.39) | ADRA1ANQO2MTNR1AMTNR1BOPRM1 | |
| SCHEMBL20170600 | 0.77 | OPRM1 (0.39) | ADRA1ANQO2MTNR1AMTNR1BOPRM1 | |
| SCHEMBL20170640 | 0.77 | HTR1A (0.34) | OPRM1HTR1A | |
| SCHEMBL20170728 | 0.76 | OPRM1 (0.37) | NQO2MTNR1AMTNR1BOPRM1 | |
| SCHEMBL20170605 | 0.76 | ADRA1A (0.35) | ADRA1AHTR1A | |
| SCHEMBL20170652 | 0.76 | OPRM1 (0.37) | NQO2MTNR1AMTNR1BOPRM1 | |
| SCHEMBL20170612 | 0.76 | ADRA1A (0.35) | ADRA1AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |