Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 19/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 19/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170797 | 0.81 | OPRM1 (0.55) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170720 | 0.81 | OPRM1 (0.55) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170658 | 0.78 | OPRM1 (0.52) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13506887 | 0.78 | OPRM1 (0.44) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13575428 | 0.78 | OPRM1 (0.44) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170791 | 0.72 | OPRM1 (0.51) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170741 | 0.72 | OPRM1 (0.51) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170615 | 0.71 | OPRM1 (0.52) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20170766 | 0.70 | OPRK1 (0.53) | OPRM1OPRD1OPRK1 | |
| SCHEMBL21741093 | 0.69 | OPRM1 (0.39) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |