Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170670 | 1.00 | OPRD1 (0.34) | OPRD1OPRM1OPRK1SIGMAR1PIN1 | |
| SCHEMBL20170836 | 0.84 | L3MBTL1 (0.31) | — | |
| SCHEMBL20170810 | 0.83 | ACHE (0.30) | ACHE | |
| SCHEMBL20170752 | 0.83 | ACHE (0.30) | ACHE | |
| SCHEMBL20170826 | 0.81 | — | — | |
| SCHEMBL20170645 | 0.80 | OPRM1 (0.39) | OPRD1OPRM1OPRK1SIGMAR1PIN1 | |
| SCHEMBL20170600 | 0.80 | OPRM1 (0.39) | OPRD1OPRM1OPRK1SIGMAR1PIN1 | |
| SCHEMBL20170616 | 0.75 | — | — | |
| SCHEMBL20170882 | 0.75 | — | — | |
| SCHEMBL13301271 | 0.75 | ANPEP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |