Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 8/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170680 | 0.82 | HCRTR1 (0.38) | HCRTR1OPRM1HTR1AOPRD1OPRK1 | |
| SCHEMBL20170855 | 0.82 | HCRTR1 (0.35) | HCRTR1OPRM1ACHEHTR1AOPRD1 | |
| SCHEMBL14617396 | 0.82 | HTR1D (0.33) | HCRTR1OPRM1HTR1AOPRD1OPRK1 | |
| SCHEMBL12945079 | 0.81 | HCRTR1 (0.44) | HCRTR1OPRM1HTR1AOPRD1OPRK1 | |
| SCHEMBL14161147 | 0.77 | HCRTR1 (0.40) | HCRTR1 | |
| SCHEMBL18473483 | 0.76 | HCRTR1 (0.46) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL14161022 | 0.75 | HCRTR1 (0.37) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL12945081 | 0.74 | OPRD1 (0.40) | OPRM1OPRD1OPRK1 | |
| SCHEMBL13151725 | 0.73 | OPRM1 (0.36) | HCRTR1OPRM1OPRD1OPRK1 | |
| SCHEMBL13067353 | 0.73 | OPRM1 (0.36) | HCRTR1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |