Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170869 | 1.00 | HTR1A (0.33) | HTR1A | |
| SCHEMBL20170738 | 0.84 | HTR1A (0.40) | HTR1A | |
| SCHEMBL20170672 | 0.79 | OPRD1 (0.37) | — | |
| SCHEMBL20170744 | 0.77 | — | — | |
| SCHEMBL20170868 | 0.77 | — | — | |
| SCHEMBL23132545 | 0.76 | — | — | |
| SCHEMBL20170740 | 0.76 | — | — | |
| SCHEMBL20170684 | 0.68 | MTNR1A (0.34) | HTR1A | |
| SCHEMBL20170616 | 0.68 | — | — | |
| SCHEMBL20170882 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |