Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20170672 | 0.89 | OPRD1 (0.37) | MTNR1AMTNR1BCA12CA1CA2 | |
| SCHEMBL20170592 | 0.86 | MTNR1A (0.40) | MTNR1AMTNR1BNPSR1 | |
| SCHEMBL20170836 | 0.69 | L3MBTL1 (0.31) | — | |
| SCHEMBL20170753 | 0.68 | GABRA1 (0.39) | MTNR1AMTNR1BDRD2 | |
| SCHEMBL20170868 | 0.65 | — | — | |
| SCHEMBL23132545 | 0.64 | — | — | |
| SCHEMBL20170740 | 0.64 | — | — | |
| SCHEMBL20170728 | 0.64 | OPRM1 (0.37) | MTNR1AMTNR1BOPRM1 | |
| SCHEMBL20170652 | 0.64 | OPRM1 (0.37) | MTNR1AMTNR1BOPRM1 | |
| SCHEMBL20170605 | 0.62 | ADRA1A (0.35) | HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453895-B1 | (+) - MORPHINANS AS ANTAGONISTS OF TOLL-LIKE RECEPTOR 9 AND THERAPEUTIC USES THEREOF | MALLINCKRODT LLC (US) | 2018-05-23 | — | — | EP | disclosed |