Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.32 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | CTSH | P09668 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24335180 | 0.75 | MEN1 (0.39) | LTA4HCTSKMEN1KMT2ASIGMAR1 | |
| SCHEMBL2994775 | 0.75 | SHBG (0.38) | CTSKCTSLCTSBCYP1A2 | |
| SCHEMBL21310235 | 0.75 | MEN1 (0.39) | LTA4HCTSKMEN1KMT2ASIGMAR1 | |
| Levopropylhexedrine SCHEMBL20780004 | 0.74 | CTSK (0.42) | LTA4HCTSKMEN1KMT2ASIGMAR1 | |
| Levopropylhexedrine SCHEMBL161851 | 0.74 | CTSK (0.42) | LTA4HCTSKMEN1KMT2ASIGMAR1 | |
| Propylhexedrine SCHEMBL28537 | 0.74 | CTSK (0.42) | LTA4HCTSKMEN1KMT2ASIGMAR1 | |
| SCHEMBL3155857 | 0.73 | CYP1A2 (0.40) | LTA4HCTSKCTSLCTSBCTSH | |
| Propylhexedrine SCHEMBL28890426 | 0.72 | CTSK (0.41) | LTA4HCTSKMEN1KMT2ASIGMAR1 | |
| Propylhexedrine SCHEMBL4900116 | 0.72 | CTSK (0.41) | LTA4HCTSKMEN1KMT2ASIGMAR1 | |
| Cyclopentamine SCHEMBL13479599 | 0.72 | CTSK (0.40) | LTA4HCTSKMEN1KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3323815-A1 | HUMAN PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE | Aerpio Therapeutics, Inc. (US) | 2018-05-23 | — | — | EP | disclosed |