Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP9X | Q93008 | 10/20 | 0.43 |
| ▸ | USP24 | Q9UPU5 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | USP5 | P45974 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882277 | 0.90 | USP9X (0.52) | USP9XUSP24UCHL1USP5GPR88 | |
| SCHEMBL10124876 | 0.82 | USP9X (0.54) | USP9XUSP24UCHL1USP5GPR88 | |
| SCHEMBL20171593 | 0.80 | USP9X (0.48) | USP9XUSP24UCHL1USP5CHRNB2 | |
| SCHEMBL20171606 | 0.79 | USP9X (0.46) | USP9XUSP24UCHL1USP5GPR88 | |
| SCHEMBL20171590 | 0.76 | USP9X (0.40) | USP9XUSP24UCHL1USP5GPR88 | |
| SCHEMBL20171652 | 0.75 | USP9X (0.45) | USP9XUSP24UCHL1USP5 | |
| SCHEMBL20171608 | 0.73 | USP9X (0.59) | USP9XUSP24UCHL1USP5CHRNB2 | |
| SCHEMBL882573 | 0.73 | USP9X (0.67) | USP9XUSP24UCHL1USP5 | |
| SCHEMBL20171649 | 0.73 | USP9X (0.49) | USP9XUSP24UCHL1USP5CHRNB2 | |
| SCHEMBL882194 | 0.73 | USP9X (0.58) | USP9XUSP24UCHL1USP5GPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619184-B1 | DEUBIQUITINASE INHIBITORS AND METHODS FOR USE OF THE SAME | UNIV MICHIGAN REGENTS (US) | 2018-05-23 | — | — | EP | disclosed |