Sugi Predict

Sugi Predict / Compounds / SCHEMBL201719

SCHEMBL201719

SCHEMBL201719

OCc1nc(-c2ccc(C(F)(F)F)cc2)cs1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 5/20 0.60
▸ ALDH1A1 P00352 5/20 0.60
▸ HDAC3 O15379 1/20 0.56
▸ HDAC4 P56524 1/20 0.56
▸ HDAC1 Q13547 1/20 0.56
▸ HDAC7 Q8WUI4 1/20 0.56
▸ HDAC2 Q92769 1/20 0.56
▸ HDAC10 Q969S8 1/20 0.56
▸ HDAC11 Q96DB2 1/20 0.56
▸ HDAC8 Q9BY41 1/20 0.56
▸ HDAC6 Q9UBN7 1/20 0.56
▸ HDAC9 Q9UKV0 1/20 0.56
▸ HDAC5 Q9UQL6 1/20 0.56
▸ LTA4H P09960 2/20 0.56
▸ MEN1 O00255 4/20 0.50
▸ KMT2A Q03164 4/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ GSTO1 P78417 1/20 0.49
▸ SCN9A Q15858 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4190251 0.88 HDAC1 (0.60) L3MBTL1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL4190992 0.85 HDAC1 (0.65) L3MBTL1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL220707 0.85 ALDH1A1 (0.55) L3MBTL1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL4522401 0.84 L3MBTL1 (0.56) L3MBTL1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL13140240 0.84 L3MBTL1 (0.60) L3MBTL1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL204739 0.84 L3MBTL1 (0.56) L3MBTL1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL14435495 0.84 LTA4H (0.60) L3MBTL1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL4512919 0.82 ALDH1A1 (0.62) L3MBTL1ALDH1A1HDAC3HDAC4HDAC1
SCHEMBL1197815 0.82 SCN9A (0.59) ALDH1A1LTA4HMEN1KMT2AKDM4E
SCHEMBL10222540 0.81 ALDH1A1 (0.58) L3MBTL1ALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 — — US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 — — US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 — — US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 — — US disclosed
US-8865736-B2 Antibacterial agents Biota Scientific Pty Ltd (AU) 2014-10-21 — — US disclosed
CN-102008459-B Antibacterial agents BIOTA SCIENT MAN 2013-05-29 — — CN disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 — — US disclosed
US-20130072520-A2 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2013-03-21 — — US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 — — US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 — — US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 — — US disclosed
CN-101404989-A Antibacterial agent PROLYSIS LTD (GB) 2009-04-08 — — CN disclosed
US-20090012097-A1 Polycyclic 1,2,3,4-Tetrahydro-Isoquinoline Derivatives and Compositions Comprising Them As Ppar Modulators IRM LLC (BM) 2009-01-08 — — US disclosed
US-20090012097-A1 Polycyclic 1,2,3,4-Tetrahydro-Isoquinoline Derivatives and Compositions Comprising Them As Ppar Modulators IRM LLC (BM) 2009-01-08 — — US disclosed
US-20090012097-A1 Polycyclic 1,2,3,4-Tetrahydro-Isoquinoline Derivatives and Compositions Comprising Them As Ppar Modulators IRM LLC (BM) 2009-01-08 — — US disclosed
EP-1996180-A1 ANTIBACTERIAL AGENTS Prolysis Limited (GB) 2008-12-03 — — EP disclosed
EP-1979347-A2 POLYCYCLIC 1,2,3,4-TETRAHYDRO-ISOQUINOLINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM AS PPAR MODULATORS IRM LLC (BM) 2008-10-15 — — EP disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 — — WO disclosed
WO-2007089557-A2 POLYCYCLIC 1, 2, 3, 4 -TETRAHYDRO- ISOQUINOLINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM AS PPAR MODULATORS IRM LLC (BM) 2007-08-09 — — WO disclosed
WO-2007089557-A2 POLYCYCLIC 1, 2, 3, 4 -TETRAHYDRO- ISOQUINOLINE DERIVATIVES AND COMPOSITIONS COMPRISING THEM AS PPAR MODULATORS IRM LLC (BM) 2007-08-09 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120122918-A1 ANTIBACTERIAL AGENTS ALK, ROS1, ARG1 L3MBTL1 297/4885ALDH1A1 787/4885HDAC3 1405/4885
US-20090012097-A1 Polycyclic 1,2,3,4-Tetrahydro-Isoquinoline Derivatives and Compositions Comprising Them As Ppar Modulators PPARG, PPARD, PPARA L3MBTL1 4441/4885ALDH1A1 1446/4885HDAC3 35/4885
US-20130072520-A2 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 L3MBTL1 703/4885ALDH1A1 800/4885HDAC3 1027/4885
US-20150191420-A1 ANTIBACTERIAL AGENTS ALK, ARG1, ROS1 L3MBTL1 377/4885ALDH1A1 740/4885HDAC3 1262/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 L3MBTL1 703/4885ALDH1A1 800/4885HDAC3 1027/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 L3MBTL1 703/4885ALDH1A1 800/4885HDAC3 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.