Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | MMP2 | P08253 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | MMP12 | P39900 | 2/20 | 0.48 |
| ▸ | MMP14 | P50281 | 2/20 | 0.48 |
| ▸ | MMP16 | P51512 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BMP1 | P13497 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27048202 | 0.95 | PKM (0.66) | PKMGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL25819157 | 0.94 | LMNA (0.53) | PKMGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL10000942 | 0.88 | LMNA (0.58) | PKMGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL14456654 | 0.88 | PKM (0.76) | PKMGAASMN1; SMN2MMP9MMP2 | |
| SCHEMBL25819149 | 0.88 | LMNA (0.58) | PKMGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL19676870 | 0.86 | PKM (0.54) | PKMGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL25841271 | 0.86 | ACACB (0.52) | PKMGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL13918868 | 0.86 | PKM (0.54) | PKMGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL19382857 | 0.86 | ACACB (0.52) | PKMGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL26998909 | 0.85 | PKM (0.53) | PKMGAAMAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129716-B1 | THERMOPLASTIC COMPOSITIONS CONTAINING MICROSPHERES | SOLVAY SPECIALTY POLYMERS USA (US) | 2018-05-23 | — | — | EP | disclosed |