Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.55 |
| ▸ | HTT | P42858 | 7/20 | 0.55 |
| ▸ | PKM | P14618 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | MMP14 | P50281 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000942 | 1.00 | LMNA (0.58) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL25819157 | 0.94 | LMNA (0.53) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL12642923 | 0.93 | SMN1; SMN2 (0.67) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL27048202 | 0.93 | PKM (0.66) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL16638686 | 0.93 | SMN1; SMN2 (0.67) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL20661662 | 0.91 | PKM (0.59) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL10066695 | 0.91 | LMNA (0.50) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL18661789 | 0.88 | ALDH1A1 (0.47) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL20171939 | 0.88 | PKM (0.59) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL10030394 | 0.88 | MAPT (0.47) | LMNAALDH1A1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220158-A1 | IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY | NATIONAL SCIENCE FOUNDATION | 2023-07-13 | — | — | US | disclosed |