Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MMP14 | P50281 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10000942 | 0.94 | LMNA (0.58) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL25819149 | 0.94 | LMNA (0.58) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL20171939 | 0.94 | PKM (0.59) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL19676870 | 0.92 | PKM (0.54) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL25841271 | 0.92 | ACACB (0.52) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL19382857 | 0.92 | ACACB (0.52) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL13918868 | 0.92 | PKM (0.54) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL12463908 | 0.89 | LMNA (0.44) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL27048202 | 0.88 | PKM (0.66) | LMNAALDH1A1MAPTGAAKDM4E | |
| SCHEMBL16638686 | 0.88 | SMN1; SMN2 (0.67) | LMNAALDH1A1MAPTGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220158-A1 | IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY | NATIONAL SCIENCE FOUNDATION | 2023-07-13 | — | — | US | disclosed |