SCHEMBL20172766

SCHEMBL20172766

CN(c1ccc(-c2ccccc2)cc1-c1ccccc1)c1cccc2c1oc1ccccc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.42
PLA2G2A P14555 4/20 0.37
PLA2G4A P47712 4/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37
HTT P42858 1/20 0.37
PGR P06401 1/20 0.35
PLA2G10 O15496 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
GGPS1 O95749 1/20 0.34
TNKS O95271 2/20 0.33
CDC14B O60729 1/20 0.33
CDC14A Q9UNH5 1/20 0.33
MEN1 O00255 1/20 0.33
CSF1R P07333 1/20 0.33
PDGFRB P09619 1/20 0.33
KIT P10721 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19163543 0.88 ALOX5 (0.43) ALOX5LMNAMAPTKMT2APOLB
SCHEMBL25937095 0.86 ALOX5 (0.39) ALOX5PLA2G2APLA2G4ALMNAMAPT
SCHEMBL22435724 0.84 ALOX5 (0.41) ALOX5PLA2G2APLA2G4ALMNAMAPT
SCHEMBL20172767 0.83 ALOX5 (0.39) ALOX5PLA2G2APLA2G4ALMNAMAPT
SCHEMBL22435727 0.82 ALOX5 (0.40) ALOX5PLA2G2APLA2G4ALMNAMAPT
SCHEMBL21976167 0.82 ALOX5 (0.40) ALOX5PLA2G2APLA2G4ALMNAMAPT
SCHEMBL21975855 0.82 ALOX5 (0.40) ALOX5PLA2G2APLA2G4ALMNAMAPT
SCHEMBL16185357 0.82 ALOX5 (0.40) ALOX5PLA2G2APLA2G4ALMNAMAPT
SCHEMBL21976147 0.82 ALOX5 (0.40) ALOX5PLA2G2APLA2G4ALMNAMAPT
SCHEMBL19163849 0.82 ALOX5 (0.40) ALOX5PLA2G2APLA2G4ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2019-05-23 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 ALOX5 695/4885PLA2G2A 4067/4885PLA2G4A 4007/4885
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, ESR1 ALOX5 2172/4885PLA2G2A 4215/4885PLA2G4A 4458/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 ALOX5 695/4885PLA2G2A 4067/4885PLA2G4A 4007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.