SCHEMBL20172767

SCHEMBL20172767

CN(c1cccc(-c2ccccc2)c1)c1cccc2c1oc1ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.39
CHKA P35790 1/20 0.38
PLA2G2A P14555 3/20 0.37
PLA2G4A P47712 3/20 0.37
TOP2A P11388 1/20 0.36
MAPT P10636 3/20 0.36
KMT2A Q03164 3/20 0.36
HTT P42858 2/20 0.36
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
CYP1B1 Q16678 2/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1A2 P05177 1/20 0.36
TNKS O95271 2/20 0.35
ABCG2 Q9UNQ0 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
AHR P35869 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19163849 0.89 ALOX5 (0.40) ALOX5CHKAPLA2G2APLA2G4ATOP2A
SCHEMBL15747049 0.88 TOP2A (0.44) ALOX5TOP2AMAPTKMT2AHTT
SCHEMBL24471688 0.86 ALOX5 (0.40) ALOX5PLA2G2APLA2G4AMAPTKMT2A
SCHEMBL24471886 0.84 ALOX5 (0.40) ALOX5PLA2G2APLA2G4AMAPTKMT2A
SCHEMBL17126317 0.84 ALOX5 (0.40) ALOX5PLA2G2APLA2G4AMAPTKMT2A
SCHEMBL20650743 0.83 ALOX5 (0.39) ALOX5PLA2G2APLA2G4AMAPTKMT2A
SCHEMBL14295689 0.83 ALOX5 (0.42) ALOX5PLA2G2APLA2G4AMAPTKMT2A
SCHEMBL14295685 0.83 ALOX5 (0.40) ALOX5PLA2G2APLA2G4AMAPTKMT2A
SCHEMBL25637800 0.83 MAPT (0.42) ALOX5MAPTKMT2ALMNACYP1A2
SCHEMBL20172766 0.83 ALOX5 (0.42) ALOX5PLA2G2APLA2G4AMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2019-05-23 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 ALOX5 695/4885CHKA 4773/4885PLA2G2A 4067/4885
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, ESR1 ALOX5 2172/4885CHKA 4611/4885PLA2G2A 4215/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 ALOX5 695/4885CHKA 4773/4885PLA2G2A 4067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.