SCHEMBL20172809

SCHEMBL20172809

CN(c1ccccc1[Si](C)(C)C)c1cccc2c1oc1c(F)cccc12

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20172862 0.89 C1R (0.32)
SCHEMBL20172860 0.88 C1R (0.31)
SCHEMBL20172817 0.86 NPC1 (0.34) NPC1RAB9A
SCHEMBL20650729 0.84 NPC1 (0.31) NPC1RAB9A
SCHEMBL20172796 0.84 MCL1 (0.35)
SCHEMBL20172802 0.82 ACHE (0.37) NPC1RAB9A
SCHEMBL20172790 0.82 ALOX5 (0.37) NPC1RAB9A
SCHEMBL20172844 0.82 ACP1 (0.34)
SCHEMBL21020278 0.81 NPC1 (0.36) NPC1RAB9A
SCHEMBL21020439 0.81 ALOX5 (0.34) NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2019-05-23 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 NPC1 3214/4885RAB9A 3113/4885
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, ESR1 NPC1 1478/4885RAB9A 2691/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 NPC1 3214/4885RAB9A 3113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.