Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14195830 | 0.86 | MAOB (0.62) | MAOBALDH1A1THRATHRBL3MBTL1 | |
| SCHEMBL4063273 | 0.86 | MAOB (0.62) | MAOBALDH1A1THRATHRBL3MBTL1 | |
| SCHEMBL2016734 | 0.85 | THRA (0.40) | MAOBALDH1A1THRATHRBCYP1A1 | |
| SCHEMBL2016739 | 0.85 | THRA (0.40) | MAOBALDH1A1THRATHRBCYP1A1 | |
| SCHEMBL13683800 | 0.85 | ALDH1A1 (0.63) | MAOBALDH1A1THRATHRBL3MBTL1 | |
| SCHEMBL4059477 | 0.82 | ALDH1A1 (0.67) | MAOBALDH1A1THRATHRBL3MBTL1 | |
| SCHEMBL2022606 | 0.80 | CNR1 (0.43) | ALDH1A1THRATHRBCNR1CNR2 | |
| SCHEMBL2019712 | 0.80 | CNR2 (0.45) | ALDH1A1THRATHRBCNR1CNR2 | |
| SCHEMBL31614853 | 0.80 | CNR2 (0.45) | ALDH1A1THRATHRBCNR1CNR2 | |
| SCHEMBL31614847 | 0.80 | CNR1 (0.43) | ALDH1A1THRATHRBCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9206230-B2 | Benzylic compound | AJINOMOTO CO., INC. (JP) | 2015-12-08 | — | — | US | disclosed |
| US-20140371424-A1 | BENZYLIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2014-12-18 | — | — | US | disclosed |
| US-8859732-B2 | Benzylic compound | AJINOMOTO CO., INC. (JP) | 2014-10-14 | — | — | US | disclosed |
| EP-2518041-A1 | BENZYL COMPOUND | Ajinomoto Co., Inc. (JP) | 2012-10-31 | — | — | EP | disclosed |
| US-20110160433-A1 | BENZYLIC COMPOUND | AJINOMOTO CO., INC. (JP) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160433-A1 | BENZYLIC COMPOUND | VIP, NGLY1, FURIN | MAOB 438/4885ALDH1A1 2463/4885THRA 3778/4885 |
| US-20140371424-A1 | BENZYLIC COMPOUND | VIP, NGLY1, FURIN | MAOB 438/4885ALDH1A1 2463/4885THRA 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.