Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.56 |
| ▸ | NMUR2 | Q9GZQ4 | 6/20 | 0.55 |
| ▸ | NMUR1 | Q9HB89 | 6/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.52 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.52 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174018 | 0.92 | OPRK1 (0.59) | MMP3MMP1OPRK1NMUR2NMUR1 | |
| SCHEMBL20174122 | 0.82 | OPRK1 (0.61) | OPRK1NMUR2NMUR1OPRM1NTSR2 | |
| SCHEMBL20174121 | 0.82 | F2 (0.54) | OPRK1 | |
| SCHEMBL18176637 | 0.81 | OPRK1 (0.79) | MMP3MMP1OPRK1NMUR2NMUR1 | |
| SCHEMBL14454334 | 0.80 | NMUR2 (0.63) | OPRK1NMUR2NMUR1OPRM1 | |
| SCHEMBL17951657 | 0.79 | NMUR2 (0.52) | OPRK1NMUR2NMUR1OPRM1 | |
| SCHEMBL13402526 | 0.78 | NMUR2 (0.62) | OPRK1NMUR2NMUR1OPRM1NTSR1 | |
| SCHEMBL31519795 | 0.77 | OPRM1 (0.69) | OPRK1OPRM1 | |
| SCHEMBL18270523 | 0.76 | OPRM1 (0.52) | OPRK1NMUR2NMUR1OPRM1 | |
| SCHEMBL13402508 | 0.76 | NMUR2 (0.62) | OPRK1NMUR2NMUR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094335-A1 | FINE-TUNE MODULATORS OF NEURONAL EXCITABILITY FOR NEUROPSYCHIATRIC DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-05-24 | — | — | WO | disclosed |