Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.61 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.51 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174121 | 0.87 | F2 (0.54) | OPRK1F2REN | |
| SCHEMBL18176637 | 0.85 | OPRK1 (0.79) | OPRK1NMUR2NMUR1NTSR2NTSR1 | |
| SCHEMBL3817152 | 0.84 | OPRM1 (0.61) | OPRK1OPRM1OPRD1F2 | |
| SCHEMBL20173733 | 0.83 | NMUR2 (0.54) | OPRK1NMUR2NMUR1OPRM1OPRD1 | |
| SCHEMBL10302843 | 0.82 | SLC6A2 (0.60) | OPRK1OPRM1OPRD1SLC6A2 | |
| SCHEMBL20174119 | 0.82 | MMP3 (0.59) | OPRK1NMUR2NMUR1OPRM1NTSR2 | |
| SCHEMBL32670190 | 0.81 | OPRK1 (0.61) | OPRK1NMUR2NMUR1OPRD1 | |
| SCHEMBL29899058 | 0.81 | OPRK1 (0.62) | OPRK1 | |
| SCHEMBL31553199 | 0.81 | SLC6A2 (0.60) | OPRK1OPRM1OPRD1SLC6A2 | |
| SCHEMBL31384596 | 0.80 | OPRK1 (0.65) | OPRK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018094335-A1 | FINE-TUNE MODULATORS OF NEURONAL EXCITABILITY FOR NEUROPSYCHIATRIC DISORDERS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-05-24 | — | — | WO | disclosed |