Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256335 | 0.86 | FAAH (0.48) | SIRT2SIRT1EPHX2FAAHSIRT3 | |
| SCHEMBL11858137 | 0.84 | ALDH1A1 (0.50) | ALDH1A1CYP3A4KDM4AFAAH | |
| SCHEMBL1755595 | 0.79 | — | — | |
| SCHEMBL18248537 | 0.79 | EPHX2 (0.54) | ALDH1A1CYP3A4SIRT2SIRT1EPHX2 | |
| SCHEMBL11176825 | 0.78 | EPHX1 (0.52) | SIRT2SIRT1EPHX2FAAHCASP2 | |
| SCHEMBL11318989 | 0.78 | EPHX1 (0.52) | SIRT2SIRT1EPHX2FAAHCASP2 | |
| SCHEMBL22365675 | 0.78 | EPHX1 (0.52) | SIRT2SIRT1EPHX2FAAHCASP2 | |
| SCHEMBL11309804 | 0.78 | EPHX1 (0.52) | SIRT2SIRT1EPHX2FAAHCASP2 | |
| SCHEMBL18248636 | 0.78 | EPHX1 (0.52) | SIRT2SIRT1EPHX2FAAHCASP2 | |
| SCHEMBL14957807 | 0.78 | EPHX1 (0.52) | SIRT2SIRT1EPHX2FAAHCASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS (GR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141965-A1 | AUTOTAXIN INHIBITORS AND USES THEREOF | ENPP2, SPINT2, SERPINB1 | ALDH1A1 4218/4885CYP3A4 4621/4885MEN1 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.