Sugi Predict

Sugi Predict / Compounds / SCHEMBL20174196

SCHEMBL20174196

SCHEMBL20174196

Cc1ccccc1-c1nc(-c2ccccc2)cc(-c2cccc(-c3ccccc3)c2)n1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H4 Q96RI1 1/20 0.48
▸ MEN1 O00255 9/20 0.47
▸ KMT2A Q03164 9/20 0.47
▸ MAPT P10636 6/20 0.47
▸ ALDH1A1 P00352 6/20 0.47
▸ HPGD P15428 5/20 0.47
▸ KDM4E B2RXH2 4/20 0.47
▸ LMNA P02545 2/20 0.47
▸ POLB P06746 1/20 0.45
▸ PKM P14618 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ ENPP3 O14638 1/20 0.44
▸ ENPP1 P22413 1/20 0.44
▸ GLA P06280 1/20 0.44
▸ TDP1 Q9NUW8 2/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ TSHR P16473 2/20 0.43
▸ ATM Q13315 1/20 0.43
▸ ADORA2A P29274 2/20 0.43
▸ ADORA1 P30542 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20174193 0.91 MEN1 (0.51) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL18731826 0.91 MEN1 (0.52) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL18731973 0.89 MEN1 (0.46) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL23615520 0.88 MEN1 (0.48) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL18731953 0.85 L3MBTL1 (0.50) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL18731941 0.84 CYP1A1 (0.59) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL13203269 0.83 ENPP3 (0.48) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL19762150 0.83 L3MBTL1 (0.52) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL19762190 0.83 L3MBTL1 (0.52) NR1H4MEN1KMT2AMAPTALDH1A1
SCHEMBL19762128 0.83 L3MBTL1 (0.52) NR1H4MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 — — US disclosed
US-10738034-B2 Spiro compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2020-08-11 — — US disclosed
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-24 — — US disclosed
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-05-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10738034-B2 Spiro compound and organic light-emitting device comprising same CRY1, NR2E3, ERG NR1H4 366/4885MEN1 611/4885KMT2A 1480/4885
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 NR1H4 170/4885MEN1 1825/4885KMT2A 719/4885
US-20180141933-A1 SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME CRY1, NR2E3, ERG NR1H4 366/4885MEN1 611/4885KMT2A 1480/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.