Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 11/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20174400 | 0.92 | S1PR1 (0.34) | S1PR1S1PR3ENPP3ENPP1 | |
| SCHEMBL20174413 | 0.91 | ALK (0.35) | ALK | |
| SCHEMBL20174415 | 0.87 | ALK (0.34) | ALK | |
| SCHEMBL20174345 | 0.86 | ALDH1A1 (0.37) | S1PR1S1PR3ENPP3ENPP1 | |
| SCHEMBL22326573 | 0.85 | S1PR1 (0.32) | S1PR1S1PR3ENPP3ENPP1 | |
| SCHEMBL20174411 | 0.85 | ALK (0.33) | ALK | |
| SCHEMBL20174316 | 0.84 | ALDH1A1 (0.34) | S1PR1S1PR3ENPP3ENPP1 | |
| SCHEMBL20174352 | 0.83 | ALDH1A1 (0.34) | ENPP3ENPP1 | |
| SCHEMBL20174358 | 0.83 | ALDH1A1 (0.36) | ENPP3ENPP1 | |
| SCHEMBL20174299 | 0.83 | ENPP3 (0.31) | S1PR1S1PR3ENPP3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-08-11 | — | — | US | disclosed |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | ALK 2665/4885S1PR1 2330/4885S1PR3 2837/4885 |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | ALK 2665/4885S1PR1 2330/4885S1PR3 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.