Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18034326 | 0.84 | LPL (0.34) | LPLLIPGPRMT5WDR77CSF1R | |
| SCHEMBL18034436 | 0.84 | LPL (0.34) | LPLLIPGPRMT5WDR77CSF1R | |
| SCHEMBL16855491 | 0.83 | PGR (0.35) | LPLLIPGPRMT5WDR77CSF1R | |
| SCHEMBL16250086 | 0.83 | PGR (0.35) | LPLLIPGPRMT5WDR77CSF1R | |
| SCHEMBL18732181 | 0.83 | LPL (0.33) | LPLLIPGPRMT5WDR77EGFR | |
| SCHEMBL18732173 | 0.82 | PGR (0.35) | LPLLIPGPRMT5WDR77CSF1R | |
| SCHEMBL20224580 | 0.82 | PGR (0.35) | LPLLIPGPRMT5WDR77CSF1R | |
| SCHEMBL20224581 | 0.82 | PGR (0.35) | LPLLIPGPRMT5WDR77CSF1R | |
| SCHEMBL20174688 | 0.82 | LPL (0.36) | LPLLIPGPRMT5WDR77CSF1R | |
| SCHEMBL20224575 | 0.82 | AHR (0.37) | LPLLIPGPRMT5WDR77CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | LG CHEM, LTD. (KR) | 2020-08-11 | — | — | US | disclosed |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEM, LTD. (KR) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10738034-B2 | Spiro compound and organic light-emitting device comprising same | CRY1, NR2E3, ERG | LPL 961/4885LIPG 2731/4885PRMT5 4609/4885 |
| US-20180141933-A1 | SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | CRY1, NR2E3, ERG | LPL 961/4885LIPG 2731/4885PRMT5 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.