Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | CCR8 | P51685 | 2/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.42 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176001 | 0.82 | COMT (0.59) | KMT2AMEN1MAPTNPC1CASP3 | |
| SCHEMBL2478261 | 0.77 | PSMD14 (0.62) | MAPTCCR1CCR8COMTCCR5 | |
| SCHEMBL454942 | 0.70 | CYP1A2 (0.55) | KMT2AMEN1MAPTRAB9ASLC40A1 | |
| SCHEMBL7548538 | 0.70 | KDM4E (0.52) | MAPTNPC1RAB9AATMCCR1 | |
| SCHEMBL17081149 | 0.70 | PTGS1 (0.52) | MAPTRAB9ARELAALDH1A1KDM4E | |
| Bromide SCHEMBL1143538 | 0.69 | CYP1A2 (0.53) | KMT2AMEN1MAPTRAB9ASLC40A1 | |
| SCHEMBL20176007 | 0.69 | PDGFRB (0.56) | KMT2AMEN1RAB9ARELAALDH1A1 | |
| SCHEMBL2471617 | 0.69 | SLC40A1 (0.47) | KMT2AMEN1MAPTNPC1RAB9A | |
| 8-Aminoquinoline SCHEMBL28223669 | 0.68 | LMNA (0.53) | KMT2AMEN1MAPTNPC1CASP3 | |
| SCHEMBL8439027 | 0.68 | SLC40A1 (0.52) | KMT2AMEN1MAPTRAB9ACCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180141911-A1 | Quinoline Derivatives for Diagnosis and Treatment of Alzheimer's Disease | NORTHEASTERN UNIVERSITY | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141911-A1 | Quinoline Derivatives for Diagnosis and Treatment of Alzheimer's Disease | MAPT, PSEN1, PSEN2 | KMT2A 2720/4885MEN1 1230/4885MAPT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.