Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29226433 | 0.81 | PTPN1 (0.47) | PTPN1CASRCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL7861321 | 0.81 | PTPN1 (0.47) | PTPN1CASRCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL29941124 | 0.81 | PTPN1 (0.47) | PTPN1CASRCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL20176100 | 0.75 | NPC1 (0.44) | KIF11SMN1; SMN2HPGDMEN1ALDH1A1 | |
| SCHEMBL20176099 | 0.75 | KMT2A (0.52) | SMN1; SMN2MEN1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL548731 | 0.74 | PTPN1 (0.50) | PTPN1CASRCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL7132144 | 0.74 | CASR (0.58) | PTPN1CASRCYP3A4CYP2D6SLC6A2 | |
| SCHEMBL20176103 | 0.72 | ALDH1A1 (0.48) | CYP3A4KIF11SMN1; SMN2HPGDMEN1 | |
| SCHEMBL20176102 | 0.72 | ATM (0.44) | KDM4ESMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL9719820 | 0.72 | PTPN1 (0.49) | PTPN1CASRCYP3A4CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450331-B2 | Functionalized cyanosilane and synthesis method and use thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2019-10-22 | — | — | US | disclosed |
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | EAST CHINA NORMAL UNIVERSITY (CN) | 2018-05-24 | — | — | US | disclosed |
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | EAST CHINA NORMAL UNIVERSITY (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | NCLN, PNN, MB | PTPN1 4263/4885CASR 3256/4885CYP3A4 1648/4885 |
| US-10450331-B2 | Functionalized cyanosilane and synthesis method and use thereof | NCLN, PNN, MB | PTPN1 4263/4885CASR 3256/4885CYP3A4 1648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.