Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20176102 | 0.91 | ATM (0.44) | SMN1; SMN2MAPK1CTNNB1WNT3ANPC1 | |
| SCHEMBL933157 | 0.76 | CYP3A4 (0.50) | ALDH1A1SMN1; SMN2CYP3A4MAPK1NPC1 | |
| SCHEMBL19265029 | 0.73 | HPGD (0.43) | ALDH1A1SMN1; SMN2HTTKIF11CYP3A4 | |
| SCHEMBL9150315 | 0.73 | CYP3A4 (0.44) | ALDH1A1SMN1; SMN2HTTKIF11CYP3A4 | |
| SCHEMBL10544610 | 0.73 | MEN1 (0.49) | ALDH1A1SMN1; SMN2HTTKIF11CYP3A4 | |
| SCHEMBL10441731 | 0.73 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2KIF11CYP3A4MAPK1 | |
| SCHEMBL29043606 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KIF11CYP3A4MAPK1CTNNB1 | |
| SCHEMBL20176101 | 0.72 | PTPN1 (0.44) | ALDH1A1SMN1; SMN2HTTKIF11CYP3A4 | |
| SCHEMBL8175237 | 0.72 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTKIF11CYP3A4 | |
| SCHEMBL9150125 | 0.72 | KIF11 (0.44) | ALDH1A1SMN1; SMN2KIF11CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450331-B2 | Functionalized cyanosilane and synthesis method and use thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2019-10-22 | — | — | US | disclosed |
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | EAST CHINA NORMAL UNIVERSITY (CN) | 2018-05-24 | — | — | US | disclosed |
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | EAST CHINA NORMAL UNIVERSITY (CN) | 2018-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180141964-A1 | FUNCTIONALIZED CYANOSILANE AND SYNTHESIS METHOD AND USE THEREOF | NCLN, PNN, MB | ALDH1A1 3188/4885SMN1; SMN2 762/4885HTT 2318/4885 |
| US-10450331-B2 | Functionalized cyanosilane and synthesis method and use thereof | NCLN, PNN, MB | ALDH1A1 3188/4885SMN1; SMN2 762/4885HTT 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.