Sugi Predict

Sugi Predict / Compounds / SCHEMBL201772

SCHEMBL201772

SCHEMBL201772

BrCc1nc(-c2ccccc2)co1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKR1B1 P15121 1/20 0.43
▸ ENPP3 O14638 6/20 0.41
▸ ENPP1 P22413 5/20 0.41
▸ HSD11B1 P28845 2/20 0.41
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ DAGLA Q9Y4D2 1/20 0.40
▸ RAB9A P51151 1/20 0.40
▸ ELANE P08246 1/20 0.39
▸ NPPA P01160 1/20 0.36
▸ MME P08473 1/20 0.36
▸ CES1 P23141 1/20 0.36
▸ HSD17B1 P14061 1/20 0.36
▸ HSD17B2 P37059 1/20 0.36
▸ ADORA2A P29274 1/20 0.35
▸ ADORA1 P30542 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ HPGD P15428 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2707288 0.81 ENPP3 (0.58) ENPP3ENPP1MEN1KMT2ARAB9A
SCHEMBL6594295 0.81 AKR1B1 (0.49) AKR1B1ENPP3ENPP1HSD11B1MEN1
SCHEMBL4150532 0.81 ALDH1A1 (0.46) AKR1B1ENPP3ENPP1HSD11B1MEN1
SCHEMBL9880273 0.81 S1PR1 (0.50) AKR1B1ENPP3ENPP1HSD11B1MEN1
SCHEMBL4142338 0.81 NOTUM (0.49) AKR1B1ENPP3ENPP1HSD11B1MEN1
SCHEMBL28956300 0.81 NOTUM (0.46) AKR1B1ENPP3ENPP1HSD11B1MEN1
SCHEMBL12064815 0.78 NPC1 (0.51) AKR1B1ENPP3ENPP1HSD11B1DAGLA
SCHEMBL8334940 0.78 S1PR1 (0.53) AKR1B1ENPP3ENPP1HSD11B1DAGLA
SCHEMBL23975591 0.77 ENPP3 (0.42) AKR1B1ENPP3ENPP1HSD11B1MEN1
SCHEMBL13335153 0.77 AKR1B1 (0.59) AKR1B1HSD11B1DAGLANPPAMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 — — US disclosed
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3 2 PHARMA LLC (US) 2023-11-02 — — US disclosed
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3 2 PHARMA LLC (US) 2023-11-02 — — US disclosed
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2023-05-23 — — US disclosed
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof 3+2 PHARMA, LLC (US) 2023-05-23 — — US disclosed
US-20210317123-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 PHARMA, LLC 2021-10-14 — — US disclosed
WO-2021183796-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF 3+2 PHARMA (US) 2021-09-16 — — WO disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 — — US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 — — US disclosed
US-20150191420-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. 2015-07-09 — — US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 — — US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 — — US disclosed
US-20120122918-A1 ANTIBACTERIAL AGENTS BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) 2012-05-17 — — US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 — — US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 — — US disclosed
US-8088791-B2 Antibacterial agents Biots Scientific Management Pty Ltd (AU) 2012-01-03 — — US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 — — US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 — — US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 — — US disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348476-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CREBBP, CREB1, EP300 AKR1B1 3683/4885ENPP3 2229/4885ENPP1 2157/4885
US-20120122918-A1 ANTIBACTERIAL AGENTS ALK, ROS1, ARG1 AKR1B1 1681/4885ENPP3 3522/4885ENPP1 2295/4885
US-20150191420-A1 ANTIBACTERIAL AGENTS ALK, ARG1, ROS1 AKR1B1 1620/4885ENPP3 3086/4885ENPP1 1830/4885
US-11655253-B2 CBP/catenin signaling pathway inhibitors and uses thereof CREBBP, CREB1, EP300 AKR1B1 3683/4885ENPP3 2229/4885ENPP1 2157/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 AKR1B1 1412/4885ENPP3 3044/4885ENPP1 2146/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 AKR1B1 1412/4885ENPP3 3044/4885ENPP1 2146/4885
US-20210317123-A1 CBP/CATENIN SIGNALING PATHWAY INHIBITORS AND USES THEREOF CREBBP, CREB1, EP300 AKR1B1 3683/4885ENPP3 2229/4885ENPP1 2157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.