SCHEMBL20177534

SCHEMBL20177534

Cc1ccc(S(=O)OCCO/N=C2/CC(c3ccc(Br)cc3)CN2)cc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.31
GPBAR1 Q8TDU6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20177592 0.76 ESRRG (0.34) GPBAR1
SCHEMBL19825307 0.66 RECQL (0.50) RECQL
SCHEMBL20041973 0.66 TSHR (0.39)
SCHEMBL20177942 0.66 DRD2 (0.32)
SCHEMBL19559484 0.65 TSHR (0.40)
SCHEMBL16785342 0.65 TSHR (0.40)
SCHEMBL20177569 0.64 ESR2 (0.37)
SCHEMBL18535350 0.62 RECQL (0.51) RECQL
SCHEMBL19687601 0.61 RECQL (0.42) RECQL
SCHEMBL6743766 0.61 RECQL (0.50) RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018092916-A1 NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE 宇部興産株式会社 2018-05-24 WO disclosed