Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 13/20 | 0.45 |
| ▸ | FPR1 | P21462 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177512 | 0.88 | FPR2 (0.59) | FPR2FPR1 | |
| SCHEMBL20177777 | 0.88 | FPR2 (0.44) | FPR2FPR1LMNAHTTALDH1A1 | |
| SCHEMBL20177528 | 0.78 | FPR2 (0.48) | FPR2FPR1 | |
| SCHEMBL20177529 | 0.77 | FPR2 (0.46) | FPR2FPR1NPC1RAB9A | |
| SCHEMBL20177640 | 0.74 | DPP4 (0.38) | HTTALDH1A1TP53 | |
| SCHEMBL20177499 | 0.74 | SMN1; SMN2 (0.37) | LMNAHTTALDH1A1NPC1MAPT | |
| SCHEMBL20177479 | 0.73 | FPR2 (0.79) | FPR2FPR1GAA | |
| SCHEMBL20177524 | 0.70 | FPR2 (0.50) | FPR2FPR1 | |
| SCHEMBL20411634 | 0.69 | FPR2 (0.63) | FPR2FPR1 | |
| SCHEMBL18264221 | 0.69 | FPR2 (0.63) | FPR2FPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |