Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177583 | 0.85 | FPR1 (0.41) | DPP4DPP7USP2KDM4EMEN1 | |
| SCHEMBL20177495 | 0.80 | USP2 (0.40) | USP2KDM4EKDM1AMEN1KMT2A | |
| SCHEMBL20177563 | 0.74 | FPR2 (0.45) | HTTTP53ALDH1A1 | |
| SCHEMBL20177500 | 0.72 | DPP4 (0.43) | DPP4DPP7KDM4ETP53TSHR | |
| SCHEMBL20177499 | 0.69 | SMN1; SMN2 (0.37) | KDM4EHTTALDH1A1 | |
| SCHEMBL20177936 | 0.68 | KDM1A (0.32) | KDM1A | |
| SCHEMBL20177716 | 0.68 | KDM1A (0.34) | KDM1A | |
| SCHEMBL20177616 | 0.62 | FPR2 (0.42) | KDM1A | |
| SCHEMBL13342393 | 0.61 | DPP4 (0.82) | DPP4DPP7 | |
| SCHEMBL28581918 | 0.61 | USP2 (0.51) | USP2KDM4EMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |