Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | TRPM5 | Q9NZQ8 | 3/20 | 0.32 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20177882 | 0.86 | KDM1A (0.35) | — | |
| SCHEMBL20177736 | 0.85 | KDM1A (0.34) | TRPM5 | |
| SCHEMBL20177903 | 0.84 | — | — | |
| SCHEMBL20177509 | 0.84 | GPBAR1 (0.34) | GPBAR1HTR2AHTR2CHTR2BOPRL1 | |
| SCHEMBL20177943 | 0.80 | HTR3A (0.36) | GPBAR1GRM5 | |
| SCHEMBL20177686 | 0.77 | — | — | |
| SCHEMBL19559541 | 0.75 | FPR2 (0.34) | FPR2 | |
| SCHEMBL20177855 | 0.75 | — | — | |
| SCHEMBL16785344 | 0.73 | FPR1 (0.35) | FPR1FPR2 | |
| SCHEMBL18117741 | 0.73 | FPR1 (0.35) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018092916-A1 | NITROGEN-CONTAINING POLYCYCLIC HETEROCYCLIC DERIVATIVE | 宇部興産株式会社 | 2018-05-24 | — | — | WO | disclosed |